Survey Frequence of ESBLs in Escherichia coli and Klebsiella pneumoniae Strains Isolated of Urinary Tract Infection
Shilla Jalalpoor Teacher of Microbiology,
Islamic Azad University Shahreza Branch,
Membership of Young Researchers Club.
Islamic Republic of Iran
Abstract:
Introduction and Objectives:
ESBLs are defined as β-lactamase capable of hydrolyzing third generation cephalosporin's and inhibited by β-lactamase inhibitor. Urinary Tract Infection (UTI) is a on of the most prevalent infection in the worldwide and is the second most common infection. Most of UTI are due to E.coli. Antibiotic resistance in ESBLs strains is one of the emerging health related problem in the world nowadays.
Materials and Methods:
The search were laboratory and performed in Azzahra and Shariaty hospitals in 2009 year in Isfahan, according to statistical formula randomly selected 91 samples from urinary infections. Bacterial identification was performed with microbiological methods. ESBLsdetermine were in two section, screening and confirming testing were respectively included by Kirby-Bauer's disc diffusion and Combining disc methods.
Conclusion:
From 91 samples frequency of E.coli and K.pneumoniae strains was respectively 84/6% and 15/4%. Frequence of ESBLs in E.coli and K.pneumoniae strains was respectively 27 samples (35/06%) and 5 samples (35.71%).
According to result there is high prevalence of ESBLs in E.coli and K.pneumoniae because third generation cephalosporin's are usually first line against to many severely infections disease. Justifiable use of will be an effective means of controlling and decreasing spread of ESBLs strains.
